Most significant findings (FDR < 0.01)
(grouped by sex and model)
CpG info EWAS results Regulatory regions1 Genes1
CpG ID Position (chrX)2 Effect size3 FDR Ensembl ID Region type Position2 Ensembl ID Description Gene ID Position2
Girls - Model 1
cg25034591 24,073,134 −0.52 3.77 × 10−3 ENSR00000245352 Promoter chrX:24,071,400-24,075,401 ENSG00000130741 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa [Source:HGNC Symbol;Acc:3267] EIF2S3 chrX:24,072,833-24,096,088
cg13866977 112,051,826 0.32 3.77 × 10−3 ENSR00001768065 Enhancer chrX:112,050,201-112,053,200 ENSG00000126016 angiomotin [Source:HGNC Symbol;Acc:17810] AMOT chrX:112,017,731-112,084,043
cg26175661 114,826,443 0.28 5.71 × 10−3 NA NA NA ENSG00000102024 plastin 3 [Source:HGNC Symbol;Acc:9091] PLS3 chrX:114,795,501-114,885,181
Girls - Model 2
cg25034591 24,073,134 −0.54 1.48 × 10−3 ENSR00000245352 Promoter chrX:24,071,400-24,075,401 ENSG00000130741 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa [Source:HGNC Symbol;Acc:3267] EIF2S3 chrX:24,072,833-24,096,088
cg13866977 112,051,826 0.33 1.48 × 10−3 ENSR00001768065 Enhancer chrX:112,050,201-112,053,200 ENSG00000126016 angiomotin [Source:HGNC Symbol;Acc:17810] AMOT chrX:112,017,731-112,084,043
Girls - Model 3
cg25034591 24,073,134 −0.52 4.46 × 10−3 ENSR00000245352 Promoter chrX:24,071,400-24,075,401 ENSG00000130741 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa [Source:HGNC Symbol;Acc:3267] EIF2S3 chrX:24,072,833-24,096,088
cg13866977 112,051,826 0.32 4.46 × 10−3 ENSR00001768065 Enhancer chrX:112,050,201-112,053,200 ENSG00000126016 angiomotin [Source:HGNC Symbol;Acc:17810] AMOT chrX:112,017,731-112,084,043
cg26175661 114,826,443 0.28 7.50 × 10−3 NA NA NA ENSG00000102024 plastin 3 [Source:HGNC Symbol;Acc:9091] PLS3 chrX:114,795,501-114,885,181
Girls - Model 4
cg25034591 24,073,134 −0.54 1.72 × 10−3 ENSR00000245352 Promoter chrX:24,071,400-24,075,401 ENSG00000130741 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa [Source:HGNC Symbol;Acc:3267] EIF2S3 chrX:24,072,833-24,096,088
cg13866977 112,051,826 0.32 1.72 × 10−3 ENSR00001768065 Enhancer chrX:112,050,201-112,053,200 ENSG00000126016 angiomotin [Source:HGNC Symbol;Acc:17810] AMOT chrX:112,017,731-112,084,043
Boys - Model 1
cg00920314 84,189,177 0.33 3.39 × 10−6 NA NA NA ENSG00000229547 ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) [Source:HGNC Symbol;Acc:28656] UBE2DNL chrX:84,189,157-84,189,896
cg04516011 84,189,179 0.26 4.96 × 10−6 NA NA NA ENSG00000229547 ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) [Source:HGNC Symbol;Acc:28656] UBE2DNL chrX:84,189,157-84,189,896
Boys - Model 2
cg00920314 84,189,177 0.32 4.61 × 10−6 NA NA NA ENSG00000229547 ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) [Source:HGNC Symbol;Acc:28656] UBE2DNL chrX:84,189,157-84,189,896
cg04516011 84,189,179 0.26 4.61 × 10−6 NA NA NA ENSG00000229547 ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) [Source:HGNC Symbol;Acc:28656] UBE2DNL chrX:84,189,157-84,189,896
Boys - Model 3
cg00920314 84,189,177 0.32 9.33 × 10−6 NA NA NA ENSG00000229547 ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) [Source:HGNC Symbol;Acc:28656] UBE2DNL chrX:84,189,157-84,189,896
cg04516011 84,189,179 0.25 9.33 × 10−6 NA NA NA ENSG00000229547 ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) [Source:HGNC Symbol;Acc:28656] UBE2DNL chrX:84,189,157-84,189,896
Boys - Model 4
cg00920314 84,189,177 0.31 1.15 × 10−5 NA NA NA ENSG00000229547 ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) [Source:HGNC Symbol;Acc:28656] UBE2DNL chrX:84,189,157-84,189,896
cg04516011 84,189,179 0.25 1.15 × 10−5 NA NA NA ENSG00000229547 ubiquitin-conjugating enzyme E2D N-terminal like (pseudogene) [Source:HGNC Symbol;Acc:28656] UBE2DNL chrX:84,189,157-84,189,896
1 NA = Not applicable
2 genome build GRCh 37
3 Color shading reflects the magnitude and the sign of the estimated effect - from dark red (strong negative effect), through beige (weak negative effect), and dark blue (strong positive effect).